Cosmelan®
Skin rejuvenation pigmentation treatments
The Mesoestetic’s Cosmelan is a world renowned depigmentation program. It is our ‘creme de la creme’ of pigmentation treatments, as it is able to treat most forms of pigmentation and delivers some of our most drastic results. Whilst it is not for the faint hearted, those who can commit to the Cosmelan journey are always very impressed and pleased with their results. The complexity of pigmentation means that no singular treatments is the best above others, as they all treat different slightly different forms of pigment and work in different ways, sometimes even a combination of these treatments is what’s needed to banish pigment.
Human skin owes its colour to a pigment – melanin. Melanin is produced in melanocytes, chromocytes located in the epidermis. These cells have special structures referred to as melanosomes where, after numerous metabolic transformations, melanin is produced. It plays an important and useful role, involving protection of the skin against harmful impact of ultraviolet radiation. Excessive accumulation of melanin causes occurrence of brown or russet spots, especially in uncovered areas such as the face, cleavage, hands and arms. Factors which support occurrence of pigment spots is the skin aging process resulting from excessive exposition to sunlight, certain individual predisposition and the influence of hormones (pregnancy, contraceptives).
Not only does the COSMELAN® treatment enable effective removal of pigment spots, but it restores smoothness and radiance to the skin. The Cosmelan treatment programme is tailored to meet the individual needs of the patient and the patient’s skin photo type. The main indication is elimination of spots with a hormonal background (melasma, chloasma) and those caused by sun damage.
Dermamelan contains more active ingredients than Cosmelan and it contains salicylic acid (which is not contained in Cosmelan). The difference in composition may suggest greater suitability of Dermamelan for oiler skin, but Cosmelan also works well in connection with this kind of skin.

What does it treat?
- Pigmentation
- Discolouration
- Melasma and Chloasma (Hormonal. Pigmentation)
- Freckles
- Old age spots
- Sun Spots
Is this a painful treatment?
During the first 2 days after the treatment the skin may be reddened and sensitive, this is a very normal reaction. You may also observe a feeling of tension and tightness. To reduce the skin discomfort sensation, you may increase frequency of moisturiser cream application.
Contraindications and adverse side effects
- Skin allergies
- Herpes
- Treatment with vitamin A derivatives
- Pregnancy and lactation
- Bacterial infections
- Viral infections
- Hypersensitivity to light
- Tendency to develop keloids
The adverse effects are usually foreseeable, moderate and temporary. These usually involve exfoliation of the skin for approximately 7-10 days, redness, tenderness, intensified acne lesions, post-treatment discolourations in case of patients who do not observe the sun protection rules.
The best way to know which treatment will be the best for you is to book in for a consultation with our skin specialist, and they can create a customised treatment plan for your skin.

Available In-clinic and Online
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